Stromectol

Stromectol (Ivermectin)

Stromectol belongs to the group of antiparasitic agents and helps fight some species of roundworms. The drug is FDA-approved and used to treat infections caused by parasites, including skin, intestinal, eye and hair. The drug has a high antiparasitic efficiency and is recommended for use only in the presence of a confirmed diagnosis. It is among the best antiparasitic drugs. There is unconfirmed data about Ivermectin ability to suppress the COVID-19 virus. However, there is no official approval for its use in coronavirus therapy.

Drug Info

• Brand Name: Stromectol
• Active Ingredient: Ivermectin
• Manufacturer: Merck & Co

The mechanism of action

The active ingredient of Stromectol is ivermectin, made of avermectins, a broad-spectrum antiparasitic agent with high activity. When ingested, Ivermectin provides a negative effect on the muscular functions and nervous system of parasites. It leads to their paralysis and death.

Ivermectin is active in some life cycles of parasites but not all nematodes. The drug also provides an anti-inflammatory effect. Despite its high toxicity to parasites, the drug is safe for mammals in therapeutic doses since it practically does not penetrate the blood-brain barrier.

Pharmacokinetics

When used orally, Ivermectin is metabolized in the liver and is excreted 99%, mainly with feces, within 12 days. 1% of the substance is excreted through the kidneys with urine. Peak concentrations after the use of a 12mg dosage were observed 4 hours after ingestion. The half-life of the drug is 18-19 hours. The bioavailability of Ivermectin increases multiple times if taken with food.

Indications

The drug is effective in treating infections, such as:

• intestinal strongyloidiasis caused by Strongyloides stercoralis
• onchocerciasis (river blindness) caused by Onchocerca volvulus
• scabies caused by Sarcoptes scabiei

Ivermectin affects developing parasites. The effectiveness of treatment depends on the correct diagnosis. The doctor may also prescribe Stromectol to treat other conditions. You can buy generic Stromectol Ivermectin to treat these pathologies, but its dosage should be further discussed with a specialist.

The composition and active ingredients

Each Stromectol tablet contains:

• active ingredient Ivermectin 3 mg
• auxiliary ingredients (microcrystalline cellulose, gelatinized corn starch, stearate, bottled magnesium hydroxyanisole, citric acid

Dosage and regimen

If you are prescribed Stromectol, buy a single dosage because, in most cases, it is taken once. The drug is available in the form of white tablets with a dosage of 3 mg. If the prescribed dosage of Stromectol is 12mg, buy 4 tablets for a single dose. The doctor determines the dosage and number of pills in each case. It depends on such factors as:

• type of infection
• weight
• height

The usual single dosage of the drug is 1 to 5 tablets, a maximum of 15 mg. It is recommended to take the medication 1 hour before or 2 hours after meals. And don't forget to wash it down with a glass of water.

The doctor also determines the number of intakes during the treatment course. Usually, two doses are taken at an interval of 8-15 days. In the case of onchocerciasis, the interval is 6 to 12 months.

Stromectol can be used both in monotherapy and in combination with other drugs (for scabies). Dosages for men and women don't differ. Using the drug is strongly not recommended in children under 5 years or weighing less than 15 kg!

In some cases, taking more than one drug dose or taking it regularly may be necessary. It is usually needed for patients with a weakened immune system. Follow your doctor’s instructions precisely. To monitor the effectiveness of Stromectol treatment, it is recommended that you regularly have your stool tested.

If you missed a dose

Since Stromectol is usually taken once, you can take it anytime, following the instructions. If you take the drug on a schedule according to the doctor’s prescription, take the missed dose as soon as you remember. If it’s time for your next dose, skip it.

Overdose

If you have exceeded your prescribed dosage, you may need medical attention. Symptoms of an overdose are:

• rash on the skin, hives
• swelling (legs, feet, ankles)
• drowsiness, dizziness, headache
• upset stomach, vomiting, abdominal pain
• loss of consciousness
• shortness of breath
• weakness and numbness of limbs
• tremor
• dilated pupils

In case of such symptoms, immediately contact the emergency department.

Side effects

Although the drug is tolerated relatively well, some people may have side effects. They may vary depending on the chosen treatment regimen. The most common complaints are:

• pain in muscles and joints
• skin rash and itching
• swelling of the legs, feet, and ankles
• aggravation of asthma
• eye redness, conjunctivitis, visual impairment
• palpitations
• dizziness
• pains in the groin, underarm and neck
• nausea, vomiting, diarrhea, constipation
• abdominal pain
• lack of appetite
• tremor

Serious side effects of Stromectol include:

• severe skin reactions (redness, blistering, peeling)
• fever and chills
• strong muscle and joint pains

Such symptoms indicate a strong allergic reaction to the drug and require immediate medical attention. Some people may develop an individual response to Ivermectin not mentioned above.

Precautions

Before taking the drug, inform the doctor if you have any allergic reactions and if you take any other medications. Care should be taken when using Stromectol in patients with liver and kidney diseases and those with HIV, AIDS or cancer that suppress the immune system.

Be careful when doing work that requires increased focus. Do not drive until you are sure the drug does not affect you negatively and your reactions have not changed.

The effect of Ivermectin on pregnancy and developing foetus is unknown. Inform your doctor if you are pregnant or are planning a pregnancy. Since the drug penetrates breast milk, its use during this period should be discussed further.

Contraindications

The main contraindications for Stromectol use are:

• allergy to Ivermectin and other components of the drug
• prevention of parasitic infections
• infection with parasites, which Ivermectin does not affect
• asthma
• taking drugs that are incompatible with Ivermectin

You can find out more about contraindications to the drug use in the instructions or from your doctor.

Interaction with other drugs

Some drugs may increase side effects or reduce the effectiveness of Stromectol if taken simultaneously. So be sure to inform the doctor if you take:

• barbiturates (phenobarbital, butalbital)
• benzodiazepines (clonazepam, lorazepam)
• valproic acid, etc.

Ivermectin can also interact with some vitamins and plant products.

Use in elderly patients

There is not yet enough data to show the difference between drug use in elderly patients compared to others. But given the presence of many different diseases, Stromectol should be used to treat parasitic infections in older people with caution. This is due to a decrease in the functions of the organs, which are negatively affected by the drug: the liver and kidneys.

Storage conditions

Stromectol should be stored in a dry, light-proof and inaccessible for kids place with a temperature below 30°C. Do not use the medication if the packaging is damaged. Also, do not use the drug if the expiration date has expired.

Сan you buy Stromectol over the counter

Stromectol is a prescription drug. A specialist should calculate its dosage. Some forms of Ivermectin (mainly for treating head lice) are available without a prescription.

How to buy Stromectol

To buy Stromectol, you can contact any pharmacy and provide your prescription. The price for the drug in various pharmacies differs slightly. But if you need the medication urgently, buy stromectol online in our pharmacy. It is much easier to buy stromectol 6 mg online than to spend time going to the brick-and-mortar pharmacy.

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